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Alcohol enhances the sedative effect of zolpidem, joint use is not recommended. Drugs that act depressingly on the central nervous system (neuroleptics, barbiturates, other sleeping pills, anxiolytics / sedatives, antidepressants with sedative action, narcotic analgesics, antitussive central action), antiepileptic drugs, general anesthetics, antihistamines with sedative effect, antihypertensive central action; baclofen; thalidomide; pizotifen – when combined, there is an intensification of the oppressive effect on the central nervous system and the risk of respiratory depression increases; buprenorphine – risk of respiratory depression; ketoconazole (a powerful inhibitor of CYP3A4) reduces the clearance of zolpidem, in connection with which it is possible to increase its sedative effect; itraconazole (inhibitor CYP3A4) – a slight, clinically insignificant change in the pharmacokinetics and pharmacodynamics of zolpidem. Rifampicin (inducer CYP3A4) accelerates metabolism, reduces the concentration and effectiveness of zolpidem.

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[b]ASK:[/b]
Does Ambien increase GABA? Yes, Ambien increases the activity of GABA (gamma-aminobutyric acid), a neurotransmitter that inhibits brain activity. This mechanism helps induce relaxation and sedation, aiding in the initiation and maintenance of sleep.

[b]What is Ambien called in Europe? In Europe, Ambien is known by the generic name zolpidem. It may also be available under different brand names depending on the country, but zolpidem is the active ingredient.[/b]

Is melatonin better than a sleep aid? Melatonin is a milder sleep aid and is often preferred for occasional sleep issues. However, for severe insomnia, prescription sleep aids like Ambien may be more effective.

[b]Is Ambien as good as Xanax? Ambien and Xanax are different medications. Ambien is a sedative-hypnotic used for sleep, while Xanax is an anti-anxiety medication. They serve different purposes and should not be compared directly.[/b]

Is zolpidem 10 mg addictive? Zolpidem can be habit-forming, especially at higher doses or with long-term use. It’s crucial to follow your doctor’s recommendations and not exceed prescribed dosages.

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